. -- Jenna Laine, Bold prediction: The Falcons, with no Cordarrelle Patterson and against a good run defense, will manage to once again top 150 rushing yards with Tyler Allgeier leading the way. The Colts, like in previous seasons, are struggling statistically on defense, ranking 31st overall. The Packers opened the season with a disastrous loss at New Orleans . -- Brooke Pryor. Dolphins 19, Titans 17 -- Cameron Wolfe, The Dolphins allowed 235 rushing yards in last year's loss to the Titans. And for fantasy managers looking to make all the right moves, Graziano and Fowler name must-start sleepers and point out potential fantasy flops of the week. Because of the injuries in the Steelers' secondary, Josh Allen is primed to jump out to a big lead early and then let the ground attack go to work to run out the rest of the game. -- Jenna Laine. Betting nugget: All four Bills games have gone under the total this season. Stat to know: Geno Smith has a 77.3 completion percentage this season, the highest by any QB through a team's first four games of a season in NFL history (min. It ranks in the bottom third of the NFL in yards allowed per carry (5.0), and the Giants -- with the NFL's leading rusher, Saquon Barkley -- run it at the second-best clip in the league (5.8 yards per carry). Weinfuss' pick: Cardinals 20, Bengals 17 With coaching staff in place, what's next for Carolina Panthers? Cardinals 30, Eagles 27 -- Tim McManus, It's hard to know what the Jaguars are going to get from QB Blake Bortles each week, and this week may be even more of a mystery because the Jaguars may be without WR Marqise Lee because of a rib injury. He has had 11 passes batted down at the line of scrimmage, six more than any quarterback in the NFL this season. Finally, Seth Walder and Eric Moody give us final score picks for every game. Theyll give up some yards and some plays. See Week 5 rankings. Betting nugget: Detroit has covered six straight road games, but it is 0-10-1 outright in its past 11 road games (0-9-1 under Dan Campbell). Eli Manning beats Philip Rivers for the first time in his career. Reiss' pick: Patriots 30, Redskins 6 The model also enters Week 5 of the 2021 season on an incredible 124-82 run on top-rated NFL picks that dates . NFL odds, Vegas lines, picks, spreads, bets, predictions for Week 5 And regardless of whos at quarterback, Adam Thielen and Stefon Diggs need to spark the Vikings' aerial attack early while the running game gets in its groove with Latavius Murray taking the reins for an injured Dalvin Cook. He is the first player with nine sacks through the first four games of a season since Kabeer Gbaja-Biamila recorded nine in 2001. Everything you want to know is here in one spot to help you get ready for a loaded weekend of NFL football. The Week 5 NFL slate is stacked with great matchups. Read more. -- Katherine Terrell, Bold prediction: Ryan Neal will take over for Josh Jones in the starting lineup and spark Seattle's struggling defense with a game-changing takeaway. Moody's pick: Chargers 27, Browns 20 But can the Colts keep possession effectively enough to pull the upset? Which QB will Colts take in Round 1? Cincinnati Bengals vs. Baltimore Ravens picks, predictions NFL Week 5 NFL Expert Picks - Super Bowl Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14 Week 15 Week 16 Week 17 Week 18 Wild Card Divisional Round Conference Championship Super Bowl hidden NFL Week 5 odds, point spreads, picks and best bets - The Washington Post -- Ben Baby. Bold prediction: With quarterback Sam Darnold (mono) sidelined for a third straight game, the Jets' epic struggles on offense will continue. Around The NFL Podcast Co-Host. (1:06). Read more. Stat to know: Daniel Jones needs two passing touchdowns and 72 passing yards to have the most in each category by a Giants quarterback in his first three NFL starts since the 1970 merger. See Week 5 rankings. Thursday night is going to be fun. NFL Week 5 odds: Colts vs. Broncos | Giants vs. Packers | Steelers vs. Bills Chargers vs. Browns | Texans vs. Jaguars | Bears vs. Vikings Lions vs. Patriots | Seahawks vs. Saints | Dolphins. Experts predict Week 5 NFL upset picks, fantasy football - ESPN DiRocco's pick: Panthers 17, Jaguars 16 -- Eric D. Williams, Bold prediction: The Broncos have not intercepted a pass this season, but they will get their first one Sunday. 198 days ago NFL Week 4 of the 2022-23 NFL season has come to a close. See Week 5 rankings. So this is a game the Chargers normally would lose, which is why Im picking them to win -- along with the fact that I believe the Giants will have trouble stopping the Bolts talented pass-rushing duo of Melvin Ingram and Joey Bosa. The Chiefs are averaging 5.2 yards per rush this season with McCoy on the field, compared to 3.3 with him off the field. Panthers QB Young all 'business now', Bold prediction: Bears rookie running back David Montgomery finally breaks through with 100 rushing yards. But the Commanders' run defense will be severely tested by Tennessee running back Derrick Henry. No, Williams isn't the greatest running back of all time -- or possibly even the best overall on his team -- but he has proven to be consistent and durable behind a strong offensive line. While he acquitted himself generally well in a tough spot when Mailata went down against the Jaguars on Sunday, Arizona should have some opportunities to affect the passer. What to know for fantasy: Through four weeks, there were 44 players with at least 25 carries. That doesnt mean theyll have an easy time against Houston rookie QB Deshaun Watson. Why Lions GM is getting high praise Betting nugget: Over the past five seasons, Miami is 13-7 ATS as a favorite. Here are some lines that could change after this week's slate concludes. Jets 20, Browns 17 -- Rich Cimini, Old friend Josh McCown is healthy and completing 70 percent of his passes, and the Jets have won two in a row with the kind of run-pass balance that the Browns should study. What to know for fantasy: Christian McCaffrey has set the bar so high that three straight games with more than 100 scrimmage yards isn't enough to put him in the good graces of fantasy managers. ET | Fox The Cardinals have allowed a league-high 20 sacks; the Bengals are right behind them at 19. NFL Expert Picks, Predictions, Lines: Week 5 - College Football News Chiefs 24, Texans 20 -- Adam Teicher, Deshaun Watson and the Texans' offense made a big statement scoring 57 points against the Titans. But to this point, Steelers quarterback Mason Rudolph hasn't been able to take advantage of the vertical game, averaging just 3.3 air yards per completion, the lowest for any quarterback with 50 completions since 2006. What to know for fantasy: Pittsburgh's Diontae Johnson owns a 20.5% target share this season from Rudolph, up from his 9.7% rate with Ben Roethlisberger under center. Teicher's pick: Chiefs 35, Colts 27 Steelers 24, Jaguars 10 -- Mike DiRocco, The Steelers' offense is poised to break out eventually; Ben Roethlisberger has only one completion of more than 40 yards this season -- which came in Week 2, his only home game. 1 in both defensive efficiency and QBR allowed in that span. Levis opens up about draft day See Week 5 rankings. Lamb has been targeted 42 times with 23 catches for 288 yards. This should be a prime spot for them to get on track, even with the uncertainty surrounding receiver Stefon Diggs. On the flip side, the Packers might have to run the ball with Aaron Jones given the turf toe injury to Davante Adams, who caught two touchdown passes in the previous meeting in Dallas. The Bucs also gave up an uncharacteristic 189 rushing yards in their 41-31 loss to the Kansas City Chiefs last week -- the most they've surrendered since 2018. However, Miami is vastly improved in that area, allowing just 3.1 yards per rush and 78 yards per game this season. Matchup rating: 56.9 | Spread: SF -3.5 (46.5), What to watch for: The 49ers are missing left tackle Joe Staley and cornerback Ahkello Witherspoon, both of whom play positions opposite Cleveland's best players in defensive end Myles Garrett (and DE/LB Olivier Vernon, depending on alignment) and receiver Odell Beckham Jr. With backups in the lineup, can the Niners neutralize two of Cleveland's biggest stars? NFL Week 5 picks against the spread and player props - The Washington Post Philadelphia is allowing a league-low 4.75 yards per pass, and the Cardinals are ranked 30th in passing yards per play (5.37). Steelers 27, Jaguars 20 -- Jeremy Fowler, The Seahawks are coming off one of the more dominant halves of football they've played under Pete Carroll, outscoring the Colts 36-3 and holding them to 32 yards in the second half last week. Unless, of course, two guys who never played with Mack in Oakland -- right tackle Trent Brown, whom the Raiders feted with a four-year, $66 million contract, and left tackle Kolton Miller, the Raiders' first-round pick a year ago -- have something to say about it and keep quarterback Derek Carr clean. Expect the Texans to feed the Jaguars a heavy dose of Pierce, especially with run-game anchor Foley Fatukasi dealing with a quad injury. -- Jeff Legwold. See Week 5 rankings. Read more. Betting nugget: Arizona is 19-9 ATS in September/October under Kliff Kingsbury (12-3 ATS in October). Moody's pick: 49ers 27, Panthers 10 He had just 14 receptions for 174 yards and zero TDs in 11 games last season. He has also been sacked 11 times, tied for the eighth most in the NFL. -- Josh Weinfuss, Bold prediction: Arizona will double its sack total on the season and take Jalen Hurts down four times. That would mean bigger roles for undrafted rookie Keelan Cole (four catches) and recently signed first-year player Max McCaffrey. 1 overall pick, are hours away from being on the clock -- which means the 2023 NFL draft has arrived. Tennessee adopted a quick-hitting passing attack last week to speed up Mariota's decision-making, which should be the way to go against a Bills defense that takes away the vertical passing game and is third in the league in allowing a 57.1 completion percentage. Another big day could be in store for Bosa here, and don't be surprised if he brings back the "flag plant" celebration he used against Mayfield in that previous meeting. It's ranked fourth in rushing yards allowed per play (3.2), while the Eagles are ranked fifth in rushing yards gained per play (4.7). Chargers 20, Giants 19 -- Eric Williams, The Giants are at home in a game they badly need to keep from imploding. Since the start of last season, 13 of the Bills' 20 games have gone under. Facebook; Twitter; Facebook Messenger; Pinterest; Email; Scoring is up across the NFL. The Bills' offense -- which has gone three-and-out on 48 percent of drives this season, second most in the NFL -- will be playing short-handed at wide receiver because of a thumb injury to No. If that's the case, the Cardinals could pull off the upset. So it is possible things don't get better for Stafford this week. Matchup rating: 52.4 | Spread: NE -15 (42), What to watch for: Can the Redskins do anything to slow the Patriots' offense? He started slow, but has run for 199 yards combined the past two weeks and ranks third in the NFL in yards after first contact at 3.21 in that time. This is a matchup of the worst passing offense in the NFL (Jets, 131 yards per game) vs. the worst passing defense (324 yards per game). Chargers-Saints point spread: Saints -8.0 (over/under 50.0) Read more. Stat to know: According to NFL Next Gen Stats data, Aaron Rodgers ranked first in completion percentage into tight windows in 2016. Since Alex Smith got injured in Week 11 of last season, it has had an NFL-high five starting QBs. The Commanders have allowed 1.17 yards after contact, also second best the past two weeks. -- Jordan Raanan. Cowboys D reaching elite levels of legendary Doomsday Defense? Bengals 13, Bills 9 -- Mike Rodak, The Bengals have a tough matchup against one of the league's best defenses (Buffalo is 10th overall), but it looks like their offense finally has begun to click in the past two weeks.
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